Interleukin‐4 and Interleukin‐17 are associated with coronary artery disease
Key Points:
- IL-4, an anti-inflammatory cytokine, is involved in lipid metabolism and plaque stabilization, but its role in CAD remains complex.
- IL-17 promotes inflammation, endothelial dysfunction, and plaque instability, contributing to CAD severity.
- Understanding IL-4 and IL-17 interactions may help develop targeted immunotherapies for CAD prevention and treatment.
Description
Interleukin-4 (IL-4) and Interleukin-17 (IL-17) play significant roles in the pathogenesis of coronary artery disease (CAD) by influencing inflammation and immune responses. Their dysregulation is linked to atherosclerosis progression and cardiovascular complications.
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